What is Rheumatoid Arthritis (RA)?
Rheumatoid Arthritis is known as an autoimmune disease which can lead to joint inflammation and pain. This condition can cause pain and inflammation in many other body parts such as eyes, lungs, heart, and blood vessels. It is also known as chronic disease. These days many people are suffering from this health condition. There are many factors that can contribute to this condition such as environmental factors and genetics. You can contact your doctor if you face any problem of joint inflammation. One study shows that such type of genes might increase the risk of RA. Many other factors can also cause this health condition, for example, viruses or bacteria, emotional stress, physical trauma, certain hormones, and smoking.
The Connection Between Rheumatoid Arthritis And Hereditary
Your immune system assumes an important job to secure you from infections, bacteria, and viruses that can lead to many diseases. In addition, researchers found that certain type of genes is responsible to control immune responses. Moreover, encountering these type of hereditary qualities builds your hazard for RA. In any case, not every person who is experiencing this condition has these type of hereditary qualities, and not every person with these types of gene qualities has RA. There is some type of genes that are essential include-:
STAT4-: This gene is responsible for activating and regulating the immune system.
HLA-: The HLA is in charge of recognizing your body’s proteins and the proteins of the contaminating organism. An individual with the HLA hereditary marker is multiple times bound to create rheumatoid arthritis than the individuals who don’t have this. This hereditary quality is one of the most critical hazard factors for RA.
TRAF1 and C5-: This type of hereditary gene is responsible to cause chronic inflammation.
PTPN22-: This hereditary quality is related to the beginning of Rheumatoid Arthritis and the creation of the illness.
Family History and Rheumatoid Arthritis
One study demonstrates that if your parents had this problem you are more likely to experience this issue. Whereas, another study shows that hereditary factor only contributes 60 to 70 percent to this condition. This condition can additionally prompt due to environmental factors. Moreover, if your siblings have this condition, you are likely to develop only 5 % of this condition.
Arthritis treatment includes medications such as steroids, NSAIDS, Disease-modifying antirheumatic drugs, and Biologic agents. These are the medicines which are useful to save your joint from further damage. Moreover, treatment of arthritis includes surgery such as tendon repair and joint fusion if you are suffering from severe pain.